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Best Pqq Supplements

10 Best PQQ Supplements for 2021

If you’re looking for the best PQQ supplements to buy this year, then you’ve come to the right place

You can also get more info by jumping to our Pyrroloquinoline Quinone Supplements Guide.

Top 10 Pyrroloquinoline Quinone Supplements

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#1 Jarrow Formulas Pyrroloquinoline Quinone S Jarrow Formulas PQQ Get it on Amazon
#2 Doctor's Best Pqq Nutritional Supplement S Doctor’s Best PQQ Get it on Amazon
#3 Health Thru Nutrition Pqq 20mg S Health Thru Nutrition PQQ Get it on Amazon
#4 Life Extension Pqq Caps With Biopqq S Life Extension PQQ Get it on Amazon
#5 Now Foods Pqq Energy Plus S Now Foods PQQ Energy Plus Get it on Amazon
#6 Swanson Pqq Pyrroloquinoline Quinone S Swanson PQQ Get it on Amazon
#7 Relentless Improvement Pqq 20mg S Relentless Improvement PQQ Get it on Amazon
#8 Absorb Health Pqq (pyrroloquinoline Quinone) S Absorb Health PQQ Get it on Amazon
#9 Piping Rock Health Products Pqq 20 Mg S Piping Rock Health Products PQQ Get it on Amazon
#10 Source Naturals Pqq Mind S Source Naturals PQQ Mind Get it on Amazon

Pyrroloquinoline Quinone (PQQ) Supplements Guide

Pyrroloquinoline quinone, commonly known as PQQ or Methoxatin, is a powerful coenzyme that displays a wide range of antioxidizing, neuroprotective, and anti-aging properties. Though research is still in its early stages, scientists believe PQQ has the potential to play a vital role in the future of medicine.

Parsley, green peppers, kiwis and countless other plants contain trace amounts of Methoxatin. The problem is that even fermented soybeans – the world’s most PQQ-rich food – can’t provide a daily serving of it. To put things into perspective, there are 61 nanograms of the coenzyme in a gram of soybeans. That means you’d have to eat over 720 pounds of fermented soy per day to ingest the recommended 20mg dose of PQQ.

Fortunately, today pure Methoxatin is readily available in the form of PQQ supplements. Of course, in order to decide whether they’re right for your diet, you should learn all the facts and understand how these supplements work. That’s why this comprehensive guide details everything you need to know about PQQ.

What is PQQ?

Because pyrroloquinoline quinone is a relatively recent discovery, some of its secondary effects may still be undiscovered. That being said, PQQ’s two main properties are impossible to ignore. Over the past decade, these properties have been thoroughly studied and tested. Here’s what we now know about them:

It’s an Antioxidant That Works On a Cellular Level.

Compounds necessary for proper protein activity in cells are called coenzymes. (Simply put, they help enzymes do their job.) In the human body, PQQ molecules act as redox coenzymes. The “redox” stands for oxidation-reduction, which implies a continuous cycle of antioxidation.
In other words, at first, PQQ breaks down during oxidation just like regular antioxidants. But then it gets recycled back into its original form and continues to revigorate the organism on a cellular level.

PQQ is also uniquely stable during this redox process. It is the only known coenzyme that goes through several thousand oxidation cycles before it leaves the body.


Though the supplement hasn’t caused adverse side effects in any of the human trials, some people may react differently than others. Once again, PQQ is a very powerful coenzyme and research is still in its relatively early stages.

In rare cases, people have reported these mild side effects:

  • headache
  • fatigue
  • drowsiness

Always speak with a medical professional or doctor before taking any supplements. Always read the product label for instructions and directions.

Taking PQQ Supplements

The majority of Methoxatin supplements come in capsules. Each capsule contains 10-20mg of pure PQQ. It’s best to start off on a light regiment, so use it every other day for a week or so.

Dosage should depend on your goals but the rule of thumb is 20mg of PQQ for every 150 lbs you weigh. The only other thing to remember is that treating inflammatory symptoms requires a higher dosage.

That being said, you should never need to ingest more than 40mg per day. A toxic dose of Methoxatin is 60mg, but there’s no reason to take that much and the coenzyme isn’t any more effective in large amounts.

What to Look For in a Good PQQ Supplement

There’s really only one factor to consider when choosing a PQQ supplement brand – whether you should look for a synthetic or an extracted version. Keep in mind that there’s absolutely no difference when it comes to molecular structure, effectiveness or viability.

  • The first option is chemically synthesized in a lab, which might sound sketchy but is actually a guarantee that you’re getting a pure, clean product.
  • The other type is extracted from fermented bacteria. Ironically enough, this is also done inside a laboratory. The only real difference is the extra safety warning on most natural PQQ packages. For some reason, the extracted compound is “not intended for women who are trying to get pregnant and lactating women.”

If you always choose organic products out of principle, go for the extract. Otherwise, you should probably opt for a synthetic version.

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