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10 Best Grape Seed Extract Supplements – Highest Ranked Brands for 2018

If you’re looking for the best grape seed extract supplements to buy this year, then you’ve come to the right place

You can also get more info by jumping to our Grape Seed Extract Supplements Guide.

Top 10 Grape Seed Extract Supplements

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#1BulkSupplements Pure Grape Seed Extract Powder-sBulkSupplements Pure Grape Seed Extract PowderMore Info
#2NOW Foods Grape Seed Extract-sNOW Foods Grape Seed ExtractMore Info
#3Olympian Labs Grape Seed Supplement-sOlympian Labs Grape Seed SupplementMore Info
#4GNC Herbal Plus Grape Seed Extract-sGNC Herbal Plus Grape Seed ExtractMore Info
#5Nature's Way Grape Seed-sNature’s Way Grape SeedMore Info
#6Source Naturals Proanthodyn Grape Seed Extract-sSource Naturals Proanthodyn Grape Seed ExtractMore Info
#7Purethentic Naturals Grape Seed Extract-sPurethentic Naturals Grape Seed ExtractMore Info
#8Jazzee Naturals Grape Seed Extract-sJazzee Naturals Grape Seed ExtractMore Info
#9Herbal Secrets Grapeseed Extract-sHerbal Secrets Grapeseed ExtractMore Info
#10BlueBonnet Super Fruit Grape Seed Extract-sBlueBonnet Super Fruit Grape Seed ExtractMore Info

Grape Seed Extract Supplements Guide

Grapes have been involved in a wide range of medical applications for centuries in European countries around the world. Only recently has the United States started implementing grade seed extract to medical practices.

The compounds found in grapes are associated with a plethora of health benefits. The juice is used for grape juice or red wine and the skin is often turned into resveratrol. It is evident that the juice and skin boost our health, but what about the seeds? As seeds contain many of the same nutrients found in both the skin and juice, studies are now being conducted to see what the seeds can offer.

What Is Grape Seed Extract?

Vitis vinifera, or most commonly known as grapes, have been implemented in medicine practices as well as food for centuries. Egyptians being the first groups of people to use grapes, they mainly used them for wine for their rich health benefits. Soon after, folk healers used grapes to create ointments to help heal common injuries, pains, and serious inflammation.

Grape seed extract comes from the seeds of red wine grapes. Once the seeds are removed from the actual grape, the oil must also be removed. The oil is extracted from the seeds using a cold press. After the oil is removed, the seeds are then crushed to a fine powder.

The healing factor within grapes is actually known as OPC, or oligomeric proanthocyanidin complexes. These are incredibly strong antioxidants.

Grapes are most commonly resemble a tall vine with jagged-looking leaves and thin bark. Grapes are known to look green, purple, or red, depending on their ripeness and type. The originated from Asia but were soon brought to Europe and North America for medical purposes and regular consumption.

Why Take Grape Seed Extract?

If it’s possible to simply pop a grape into your mouth, a relevant question becomes, Why take grape seed extract? Not everyone is able to drink red wine and not everyone has access to grapes.

If you’re unable to drink red wine and can’t eat grapes, you can still reap the benefits associated with grapes in the form of grape seed extract and resveratrol. These extracts come in the form of liquid, tablets or capsules and can be easily ingested.

Proposed Uses of Grape Seed Extract

Like the juice and skin, grape seed extract has also been shown to carry numerous benefits. Some of the conditions grape seed extract may help with include:

  • High blood pressure: In a study at the University of California at Davis, 24 adults with prehypertension were divided into three groups. One group received a placebo, or fake treatment. Another group received 150mg/day of grape seed extract. And the third group received 300 mg/day of grape seed extract. After four weeks, the blood pressure had dropped for those taking 150mg/day and 300mg/day of the grape seed extract. There were no blood pressure changes in the group given a placebo.
  • Circulation: The active ingredient in grape seeds is oligomeric proanthocyanidins or OPCs. Procyanidins, specifically, seems to have an effect on blood circulation, and grape seed extract contains up to 78% by weight of procyanidins. When grape seed extract was given to participants, a decrease in blood clotting was observed.
  • Anti-oxidation: Although we need oxygen to live, oxygen does contribute to the damage of our cells. This process of continual damage is known as oxidation. An antioxidant slows down the process of oxidation or removes the oxidizing agents, altogether. Grape seed extract seems to offer anti-oxidation benefits in a study with 20 volunteers. Five volunteers received a placebo daily and 15 volunteers received 300mg/day of grape seed extract. After five days, anti-oxidation results were seen with those who were given the grape seed extract.
  • Chloasma: Chloasma is a skin condition where brown patches appear on the face. In a study conducted on 12 women, grape seed extract reduced the brown patches on their skin. The grape seed extract was given to the women over a period of six months. After the six-month period, the grape seed extract seemed to improve or slightly improve their chloasma.
  • Swelling due to injury: The proanthocyanidin in grape seed extract may also help with swelling. In a study conducted on Japanese women, the proanthocyanidin helped reduce leg swelling after long periods of sitting. The study showed that there was a decrease in leg volume and a decrease in leg fluid. There was also an increase in blood flow circulation.


There are a few side effects associated with taking grape seed extract supplements. Side effects can include dizziness, nausea, itchy scalp, and headaches.

If you are allergic to grapes, you should not take grape seed extract supplements. You should also speak to your doctor before taking these supplements if you have high blood pressure or have a bleeding disorder. If this is the case for you, taking grape seed extract supplements can be risky. These supplements are generally not recommended for women who are pregnant or breastfeeding. There is not sufficient evidence to determine whether or not it is safe, so it is best to stay away.

Additionally, if you regularly take certain medications, talk to your doctor before beginning to take grape seed extract supplements. These supplements may interact negatively with drugs including NSAID painkillers like Advil and Aleve, blood thinners, cancer treatments, some heart medications, and more.

Always speak with a medical professional or doctor before taking any supplements. Always read the product label for instructions and directions.

Taking Grape Seed Extract Supplements

You can find grape seed extract supplements in a number of different forms including liquid, tablets, and capsules. You should always speak with your primary care physician to discuss the proper dosing for your needs. You can also refer to the instructions on the label of your supplement for a guideline. In general, the dosing will be as follows.

Things to Look for in a Good Grape Seed Extract Supplement

Grape seed extract supplements are available in various forms, most popularly as tablets, capsules, or liquid. You can easily find these supplements at your local health food store or online. Be sure you purchase your supplement from a trusted manufacturer that employs only the best practices when making their supplements.

You should never buy supplements that contain synthetic chemicals that may be dangerous to your health. These ingredients include benzethonium chloride, methylparaben, and triclosan. In general, the grape seed extract supplement should only contain two ingredients, grape seed extract, and vegetable glycerin.

No matter what form you take the supplement in, there are certain standardized ingredients that you should look for.

Purchase supplements that hold between 40% and 80% proanthocyanidins and has an OPC content of at least 95%.

You should also be sure to store your supplements away from direct sunlight and heat. This will keep them the freshest for the longest.

If you do not wish to take grape seed extract in the form of a supplement, you can also eat the seeds out of the grapes. But be careful, they are very bitter!

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