Home / Plant Based Supplements / 10 Best Grape Seed Extract Supplements – Reviewed & Ranked for 2017
Please Note: We are compensated if you buy anything through the links in this article.

10 Best Grape Seed Extract Supplements – Reviewed & Ranked for 2017

If you’re looking for the best grape seed extract supplements to buy this year, then you’ve come to the right place

You can also get more info by jumping to our Grape Seed Extract Supplements Guide.

Top 10 Grape Seed Extract Supplements

#1 BulkSupplements Pure Grape Seed Extract Powder-s BulkSupplements Pure Grape Seed Extract Powder More Info
#2 NOW Foods Grape Seed Extract-s NOW Foods Grape Seed Extract More Info
#3 Olympian Labs Grape Seed Supplement-s Olympian Labs Grape Seed Supplement More Info
#4 GNC Herbal Plus Grape Seed Extract-s GNC Herbal Plus Grape Seed Extract More Info
#5 Nature's Way Grape Seed-s Nature’s Way Grape Seed More Info
#6 Source Naturals Proanthodyn Grape Seed Extract-s Source Naturals Proanthodyn Grape Seed Extract More Info
#7 Purethentic Naturals Grape Seed Extract-s Purethentic Naturals Grape Seed Extract More Info
#8 Jazzee Naturals Grape Seed Extract-s Jazzee Naturals Grape Seed Extract More Info
#9 Herbal Secrets Grapeseed Extract-s Herbal Secrets Grapeseed Extract More Info
#10 BlueBonnet Super Fruit Grape Seed Extract-s BlueBonnet Super Fruit Grape Seed Extract More Info

Grape Seed Extract Supplements Guide

Grapes have been involved in a wide range of medical applications for centuries in European countries around the world. Only recently has the United States started implementing grade seed extract to medical practices to help treat a number of diseases and health conditions. In fact, grape seed extract has also shown to be beneficial to helping cure cardiovascular disease. In addition, the extract has also shown to help reduce injury swelling as well as an array of eye diseases.

What Is Grape Seed Extract?

Vitis vinifera, or most commonly known as grapes, have been implemented in medicine practices as well as food for centuries. Egyptians being the first groups of people to use grapes, they mainly used them for wine for their rich health benefits. Soon after, folk healers used grapes to create ointments to help heal common injuries, pains, and serious inflammation. Certain types of unripe grapes were also used to help treat dry or sore throats as well. Ripe grapes, on the other hand, were used to help treat certain diseases such as smallpox, cancer, etc.

The healing factor within grapes is actually known as OPC, or oligomeric proanthocyanidin complexes. These incredibly strong antioxidants were used to help treat certain diseases and skin conditions from cancer to aging wrinkles.
Recent studies have also shown that regularly consuming grade seed extract can also help the body dispose of radicals that can damage the body’s DNA and further cause cell degeneration. In fact, scientists also believe these ‘radicals’ can be the lead cause of certain health problems such as cancer and heart disease.

Grapes are most commonly resemble a tall vine with jagged-looking leaves and thin bark. Grapes are known to look green, purple, or red, depending on their ripeness and type. The originated from Asia but were soon brought to Europe and North America for medical purposes and regular consumption.

Benefits of Grape Seed Extract

With more and more research piling in, grade seed extract is shown to have greater health impacts. Not only being able to treat common ailments and diseases, but also being able to rejuvenate flexibility in tissues, arteries, and joints in older people with lower cartilage and tissue.

In addition, grape seeds also show a lot of improvement in blood and artery circulation, along with these added growing benefits to the human body. This extract has also been proven to be beneficial when treating

High Blood Pressure:

Antioxidants located in grape seed extract can help reduce high blood pressure and further protect blood vessels from added damage. In addition, it has also shown to help lower blood pressure from those with metabolic syndrome and dilating damaged blood vessels.

Plus, a recent study also showed that a modified version of a grape seed extract drink greatly helped improve high blood pressure for those suffering from pre-hypertension with just one single dose.

Chronic Venous Insufficiency:

In a study, those suffering from Chronic Venous Insufficiency, or CVI showed reduced symptoms within 10 days of consuming grape seed extract. In fact, nearly 80 percent of the patients involved in the study noticed their symptoms drop significantly than those who were not using the supplement.

Bone Strength:

Grape seed extract is known for helping improve bone strength and formation thanks to recent animal studies.

Swelling (Edema):

The University of Maryland Medical Center conducted a test to show that grape seed extract helps reduce leg swelling after sitting for an elongated period of time. Another test also showed that those with sports injuries suffered less swelling under grape seed extract that players who were not taking it.

Cognitive Decline:

Recent animal studies have shown that grape seed extract can help reduce and reverse the effect of Alzheimer’s disease. It also showed to help reduce oxidative stress and protect most of the mitochondrial function.

Oral Health:

Grape seed extract can help lower the demineralization of cavities and can even help reverse or stop early signs of tooth decay. This overall shows that grape seed extract plays an instrumental role in everyday oral health.


When taken with regular exercise, grape seed extract helped to treat some of the symptoms associated with diabetes. This includes improvements in weight loss, blood pressure, lipid profiles, and other complications that are common with diabetes. The grape seed extract and exercise treatment were more effective than when either of those was taken alone.
According to some researchers, grape seed extract may also be helpful for:

  • Protecting elastin and collagen in the skin
  • Healing hemorrhoids
  • Making night vision better
  • Guarding the body against bacterial pathogens and oxidative rancidity

Are There any Side Effects?

There are a few side effects associated with taking grape seed extract supplements, however, they are generally considered safe. Side effects can include dizziness, nausea, itchy scalp, and headaches.

If you are allergic to grapes, you should not take grape seed extract supplements. You should also speak to your doctor before taking these supplements if you have high blood pressure or have a bleeding disorder. If this is the case for you, taking grape seed extract supplements can be risky. These supplements are generally not recommended for women who are pregnant or breastfeeding. There is not sufficient evidence to determine whether or not it is safe, so it is best to stay away.

Additionally, if you regularly take certain medications, talk to your doctor before beginning to take grape seed extract supplements. These supplements may interact negatively with drugs including NSAID painkillers like Advil and Aleve, blood thinners, cancer treatments, some heart medications, and more.

How to Take Grape Seed Extract Supplements

You can find grape seed extract supplements in a number of different forms including liquid, tablets, and capsules. You should always speak with your primary care physician to discuss the proper dosing for your needs. You can also refer to the instructions on the label of your supplement for a guideline. In general, the dosing will be as follows.

For Adults:

When taking a liquid supplement, the recommended dosage is ten to twelve drops per five ounce glass of water. Liquid supplements can be taken one to three times per day.

When taking tablets or capsules, the recommended dosage is between 100 and 200 milligrams taken one to three times a day. The exact amount will depend on why you are taking the supplement and how strong you need it to be.

Things to Look for in a Good Grape Seed Extract Supplement

Grape seed extract supplements are available in various forms, most popularly as tablets, capsules, or liquid. You can easily find these supplements at your local health food store or online. Be sure you purchase your supplement from a trusted manufacturer that employs only the best practices when making their supplements.

You should never buy supplements that contain synthetic chemicals that may be dangerous to your health. These ingredients include benzethonium chloride, methylparaben, and triclosan. In general, the grape seed extract supplement should only contain two ingredients, grape seed extract, and vegetable glycerin.
No matter what form you take the supplement in, there are certain standardized ingredients that you should look for.

Purchase supplements that hold between 40% and 80% proanthocyanidins and has an OPC content of at least 95%.

You should also be sure to store your supplements away from direct sunlight and heat. This will keep them the freshest for the longest.

If you do not wish to take grape seed extract in the form of a supplement, you can also eat the seeds out of the grapes. But be careful, they are very bitter!

Note: Always speak with your doctor before taking any supplements featured on this website. This article has not been written, reviewed or endorsed by a medical professional and may not be used to diagnose or treat any medical conditions.