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Best Goldenseal Root Supplements

10 Best Goldenseal Root Supplements for 2021

If you’re looking for the best goldenseal root supplements to buy this year, then you’ve come to the right place

You can also get more info by jumping to our Goldenseal Root Supplements Guide.

Top 10 Goldenseal Root Supplements

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#1 Nature's Way Goldenseal Herb S Nature’s Way Goldenseal Herb Get it on Amazon
#2 Pure Mountain Botanicals Organic Goldenseal Root Capsules S Pure Mountain Botanicals Organic Goldenseal Root Get it on Amazon
#3 Nature's Answer Alcohol Free Goldenseal Root, 1 Fluid Ounc S Nature’s Answer Alcohol-Free Goldenseal Root Get it on Amazon
#4 Herb Pharm Certified Organic Goldenseal Extract S Herb Pharm Certified Organic Goldenseal Extract Get it on Amazon
#5 Now Foods Goldenseal Root 500mg S NOW Foods Goldenseal Root Get it on Amazon
#6 Solaray Goldenseal Root Capsules S Solaray Goldenseal Root Capsules Get it on Amazon
#7 Nature's Bounty Echinacea & Goldenseal Plus S Nature’s Bounty Echinacea & Goldenseal Plus Get it on Amazon
#8 Nature's Way Echinacea Goldenseal Extract 1 Oz Liquid S Nature’s Way Echinacea-Goldenseal Extract Get it on Amazon
#9 Gaia Herbs Echinacea Goldenseal Supreme, Alcohol Free, 1 Ounce Bottle S Gaia Herbs Echinacea Goldenseal Supreme Get it on Amazon
#10 Herbal Secrets Echinacea & Goldenseal Root S Herbal Secrets Echinacea & Goldenseal Root Get it on Amazon

Goldenseal Root Supplements Guide

What is Goldenseal Root?

Goldenseal is an herb native to the eastern United States and southeastern Canada. A member of the buttercup family, goldenseal grows annually. Goldenseal is a top-selling herb, prized for its medicinal properties.

Also known as yellow puccoon, yellowroot and orangeroot, goldenseal once grew abundantly in the wild, thriving in deciduous forests spanning from Quebec to northern Georgia and west to Missouri.

Most goldenseal root in over-the-counter supplements comes from herbs grown on farms, due to overharvesting in the wild. The North American version has a distant Japanese cousin, although botanists agree that the latter is a different genus entirely.

Goldenseal root is available in multiple forms, including:

  • Tablet
  • Capsule
  • Tea
  • Extract
  • Mouthwash
  • Topical applications, such as creams and ointments

Preparation of goldenseal for medicinal use entails drying the herb’s rhizomes (roots), grinding the roots and using the powder as required. The roots’ active ingredients include several alkaloids. Alkaloids are organic plant-based compounds that act markedly on human physiology. Some of the main alkaloids isolated and studied thus far are:

  • Hydrastine
  • Berberine
  • Berberastine
  • Hydrastinine
  • Tetrahydroberberastine
  • Canadine
  • Canalidine

There isn’t universal agreement within the medical community that goldenseal root and its active constituents actually work.


Goldenseal may be possibly safe for most adults when taken orally as a singular dose.

For example, some individuals find even moderate formulations of goldenseal root too astringent for their mucous membranes. If you’re using a topical form, douche or mouthwash, perhaps try a preliminary spot test to assess tolerance.

Goldenseal root does have some associated precautions worth considering. It is not advisable for pregnant or nursing women. Consult your doctor before trying goldenseal root if you have liver issues, high blood pressure or heart disease.

Goldenseal root potentially interacts with certain types of drugs, including:

  • Chemotherapy drugs
  • Anticoagulants
  • Heart drugs
  • HIV drugs

You may experience photosensitivity following a bout of goldenseal root supplementation. To date, this particlar reaction has only every occurred among a small population.

Goldenseal root is not recommended for children or infants. In infants, goldenseal root exacerbates the symptoms of jaundice. High doses can cause toxicity and even death in adults.

Always speak with a medical professional or doctor before taking any supplements. Always read the product label for instructions and directions.

Taking Goldenseal Root

You can take goldenseal root in any of its available forms. It is not uncommon to purchase the dried, ground roots for DIY preparations of tea, ointment, mouthwash, extract and douche.

There are no hard and fast rules for optimal amounts to take. At the onset of cold or flu, Dr. Christopher Hobbs recommends three to four capsules, or one full dropper of liquid, or one powdered extract capsule every three hours.

Lower your dosages or discontinue use entirely at the first appearance of toxicity symptoms. Some symptoms of goldenseal root toxicity are

  • Vomiting
  • Nausea
  • Stomach cramps
  • Difficulty breathing
  • Paralysis
  • Nervousness
  • Depression

What to Look For in a Good Goldenseal Root Product

There are several criteria that a good goldenseal root supplement should have. Many of these criteria apply to choosing other herbs and dietary supplements in general. First, look for supplements with labels that fully disclose ingredients, amounts per serving and (even better) the organic sources of active ingredients.

Make sure the product is indeed goldenseal root. There are herbal “complexes” available containing proprietary blends that utilize other parts of the herb. The root contains most of the active constituents tested in research and studies.

Herbal supplements that receive high marks and favorable reviews and stars on supplement websites generally indicate a respectable, effective product. Word of mouth is still the truest, strongest assessment.

Endorsements from trusted authorities, such as Dr. Andrew Weil, fitness professionals and celebrities unaffiliated in any way with the endorsed product are another trustworthy indicator of a product’s efficacy.

Lastly, look for awards, citations and ratings, such as Supplement Awards or GMP (Good Manufacturing Practice). These industry awards and citations are often adequate gauges of a product’s consistency and potency as well as the manufacturer’s quality levels and business practices.

Important Notice: The information on is intended for entertainment purposes only and and does not constitute professional, medical or healthcare advice or diagnosis, and may not be used as such. The information on this site is not written, reviewed or endorsed by a medical professional, and is only to be used at your own risk. Make sure to follow label instructions for whichever product you purchase. does not assume liability for any actions undertaken after reading this information, and does not assume liability if one misuses products featured on this website. Always consult your doctor before using any products you see on this website. The results may vary about any product effectiveness.