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Best Lysine Supplements

10 Best Lysine Supplements – Ranked & Reviewed for 2017

If you’re looking for the best lysine supplements to buy this year, then you’ve come to the right place

You can also get more info by jumping to our Lysine Supplements Guide.

Top 10 Lysine Supplements

#1 Now Foods L Lysine S NOW Foods L-Lysine More Info
#2 Solgar L Lysine S Solgar L-Lysine More Info
#3 Source Naturals L Lysine S Source Naturals L-Lysine More Info
#4 Solaray L Lysine S Solaray L-Lysine More Info
#5 Country Life L Lysine S Country Life L-Lysine More Info
#6 Spring Valley L Lysine S Spring Valley L-Lysine More Info
#7 Pure Encapsulations L Lysine S Pure Encapsulations L-Lysine More Info
#8 Thorne Research L Lysine S Thorne Research L-Lysine More Info
#9 Superior Labs L Lysine S Superior Labs L-Lysine More Info
#10 Designs For Health L Lysine S Designs For Health L-Lysine More Info

Lysine Supplements Guide


What is Lysine?

Lysine, scientific name diaminohexanoic acid or alpha-epsilon-diaminocaproic acid, is an essential amino acid, which means that the body requires it for daily function and maintenance. Lysine cannot be synthesized by the body’s metabolic processes so this amino acid must be obtained either through diet or through supplements.

Lysine was discovered in 1889 as a component of casein, which is a protein in milk. It’s commonly added to animal feed in order to insure adequate amounts in the human diet although some individuals may require supplemental lysine. Vegetarians can obtain lysine through supplements or through consumption of beans, cheese and other dairy products, eggs, lentils, nuts, soy, and seeds. Vegans may require supplements in order to obtain adequate amounts of lysine in their diet since they don’t consume dairy products or eggs.

After ingestion, lysine is transported by the blood stream to the liver, where it is then broken down, or catabolyzed, and released to other organs and systems of the body. Depending on the individual, this process can take from four to six hours to complete.

Lysine’s bio-availability from foods may be reduced by their preparation methods. Dry cooking at high heat, cooking in combination with fructose or glucose, or in combination with yeast and/or sucrose can all reduce the bio-availability of lysine in food.

Benefits of Lysine

In addition to treating some ailments and infections, lysine is necessary for calcium absorption in the intestines and it prevents calcium excretion through the kidneys.

Those who suffer from chronic cold sores, shingles, or similar infections are advised to take supplemental lysine on a regular basis. Preliminary research indicates that this amino acid may be helpful in slowing or preventing the development of osteoporosis. It’s also shown promise in improving anxiety, lowering blood glucose levels, and increasing muscle mass.

Lysine is beneficial for the skin and has shown to be effective in combating acne, which has been attested to by numerous users.

Some evidence indicates that lysine may help reduce hair loss for the same reason it’s beneficial for the skin. This occurs because the body’s production of collagen and keratin are tied to the body’s levels of the amino acids glycine, lysine, methionine, and proline. The body synthesizes none of these amino acids so they must be obtained from food and/or nutritional supplements.

Some research has indicated that lysine may play a role in alleviating angina; lysine acetylsalicylate is used as an analgesic and detoxifying agent for those who are recovering from a heroin addiction. Lysine is essential for the production of carnitine, a dipeptide made from methionine and lysine and responsible for the conversion of fatty acids into energy.

Lysine is a vasodilator, which means it opens the blood vessels. Lysine clonixinate has been successful in the treatment of migraines, and preliminary results show that lysine has promising effects on the cardiovascular system.

Lysine is available in several forms, such as:

  • L-Lysine
  • Lysine HCl
  • Lysine acetylsalicylate
  • Lysine clonixinate
  • Lysine oxidase
  • Lysine succinate
  • Powder form

A medical professional may prescribe a specific type of lysine, depending on the ailment, but lysine HCl may be helpful as a regular dietary supplement.

Are There Any Side Effects?

Although lysine is safe to take and there are usually few or no side effects, there are some caveats and contraindications. A dosage above nine grams, or 9000 mg, per day may cause stomach pain, nausea, or diarrhea. Some users have reported constipation when taking lysine. Others have indicated the presence of greasy stools, although that was associated with a high-fat diet, and a reduction in fat intake alleviated the problem.

Occasionally, elevated ketones will present in those who take a lysine supplement. Usually increasing water intake and reducing slightly the dosage of lysine has corrected the problem.

Lysine may be transmitted through breast milk, so lactating mothers should inform their medical professional if they are taking lysine supplements. When used in combination with iron and vitamin supplements, some pregnant women showed elevated hemoglobin levels. Pregnant women should inform their medical professionals if they are taking supplemental lysine.

Using calcium supplements in conjunction with lysine supplements may result in an elevated level of calcium in the body. Elevated aminoglycoside toxicity may also occur when taking supplemental lysine.

Arginine increases the proliferation of some virus cells, lysine is its antagonist, so taking lysine will decrease the level of arginine in the body.

Lysine oxidase has shown promise in the treatment of some types of cancer cells, specifically colorectal cancer and leukemia. Study results showed that between 25 and 90 percent of cancer cells were destroyed, depending on the subject and the cancer.

One report of Fanconi syndrome, which is a rare disorder of kidney functions, and tubulointerstitial nephritis has been reported by a user who took lysine supplements for five years as a treatment for chronic viral infection. Other information, such as diet, overall health, other medications, and so forth, is not indicated.

Since lysine is absorbed slowly into the tissues, high doses are unlikely to cause deleterious side effects but should be discussed with a medical professional. Before giving lysine to a child, a medical professional should be consulted.

How to Take Lysine

As a supplement, lysine should be taken either with food or without but should not be taken in combination or conjunction with calcium supplements. The typical dose for a person who weighs 150 lbs would be 800 mg daily. Some health professionals recommend a maintenance regimen of 1000 mg daily, and 1000 mg three times per day when treating a flare up of viral infections such as cold sores, shingles, or similar. Treatment dosages for flare ups can reach 9000 mg per day, but should be under the supervision of a medical professional.

The optimal outcome is to initiate a three-times-per-day dosage as soon as the tingling or itching of the flare up is noticed. Waiting until the flare up has fully presented can delay the healing process unnecessarily.

Although taking too much lysine may not have undue and adverse side effects, it can result in elevated cholesterol or gall stones. Those who have gall bladder issues or have liver or kidney disease should consult with a medical professional before taking lysine supplements.

Many prescription remedies are available for the treatment chronic viral infections. However, lysine is the body’s natural medicine for treatment of some viruses and may therefore be the best instrument for treating them.

What to Look for in a Good Lysine Supplement

A good lysine supplement will have no fillers. It should contain lysine HCl, or whatever other form the label indicates, and no other ingredients except as are contained in the capsule itself. It should not be made from soy or contain other allergens, such as wheat, gluten, egg, fish, shellfish, tree nuts, or any other common allergens.

Buy a reputable brand that is manufactured in the U.S. Other countries may have less stringent manufacturing processes and produce a product that may be impure. Be sure to buy pharmaceutical grade lysine. Some lysine tablets are large, so if ingestion is an issue, it might be advisable to purchase a greater quantity of smaller tablets.

Not all capsules are vegetarian. Those who are vegan or vegetarians should verify that the gelatin is indeed made without animal products or opt for tablets.

Those with digestive issues might benefit from free form lysine. This means that the lysine can immediately be assimilated into the body without the usual four to six hours of digestive time. This can also benefit those who are treating an outbreak or an impending outbreak, since the lysine will begin to work immediately in the body. Free form lysine is also hypoallergenic, so those with food sensitivities or allergies may prefer to use free form lysine over other formats.

Note: Always speak with your doctor before taking any supplements featured on this website. This article has not been written, reviewed or endorsed by a medical professional and may not be used to diagnose or treat any medical conditions.