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Best Glycine Supplements

10 Best Glycine Supplements – Reviewed & Ranked for 2017

If you’re looking for the best glycine supplements to buy this year, then you’ve come to the right place

You can also get more info by jumping to our Glycine Supplements Guide.

Top 10 Glycine Supplements

#1 Now Foods Glycine 1000mg S Now Foods Glycine More Info
#2 Bulksupplements Pure Glycine Powder S BulkSupplements Pure Glycine Powder More Info
#3 Life Extension Glycine Vegetarian Capsules S Life Extension Glycine Vegetarian Capsules More Info
#4 Thorne Research – Glycine S Thorne Research – Glycine More Info
#5 Source Naturals Glycine S Source Naturals Glycine More Info
#6 Best Naturals Glycine S Best Naturals Glycine More Info
#7 Pure Encapsulations – Glycine S Pure Encapsulations – Glycine More Info
#8 Solgar Glycine Vegetable Capsules S Solgar Glycine Vegetable Capsules More Info
#9 Douglas Laboratories – Glycine S Douglas Laboratories – Glycine More Info
#10 Pure Encapsulations Pure Tranquility Liquid S Pure Encapsulations – Pure Tranquility Liquid More Info

Glycine Supplements Guide


Sometimes with our busy lifestyles or the lack of availability of certain foods, it can be difficult to obtain all of the nutrients your doctor recommends for you to consume daily through your diet.

This is where supplements can help. Used correctly, they can complement your diet to fill in the nutritional gaps that you are unable to fill with your meals. Other supplements can be used to alleviate certain medical conditions naturally.

One such supplement is glycine. To help you decide if glycine is right for you, below is all you need to know about what are glycine supplements, their benefits and possible side effects, how to incorporate them as a part of a healthy lifestyle, and what you should look for when shopping for a good glycine supplement.

What Is a Glycine?

Even if you have never heard of glycine before reading this article, your entire body needs it in order to run efficiently. According to Dr. Axe, glycine can be found in your brain, skin, muscles, and connective tissues such as ligaments and tendons.

This amino acid supports digestion, the nervous system, breaks down glycogen to provide energy to your cells, forms collagen (the ingredient that keeps your skin firm and supple), and boosts your immune system. It isn’t exaggerating to say that your body couldn’t function without this important amino acid.

As an amino acid, glycine is also one of the important ingredients to creating protein. Your body can make some glycine naturally, but other sources come from protein sources such as animal products (meat and dairy) and legumes (beans and lentils). However, these food sources only provide a small amount of glycine—the average diet only consists of 2 grams of glycine daily.

While this is enough to keep your body running at a healthy level, if you want to take advantage of the extra health benefits of glycine, a higher dose is required. You can get this higher dosage by taking glycine supplements, which are known to be a safe and effective way to consume more glycine than is possible to obtain from dietary sources.

Benefits of Glycine Supplements

Evidence suggests that glycine has even more health benefits beyond all the support it provides in keeping your body running, though more studies must be performed in order to back up these initial findings. Still, as WebMD points out, this supplement holds a lot of promise in the medical community. Some of these promising health benefits revealed by research include:

  • Treatment for Schizophrenia: One of the most promising studies indicates that at higher doses (15 to 60 grams a day), glycine can enhance the effects of treatment for schizophrenia when paired with most schizophrenia medications. However, that same research suggests that high doses of glycine should never be paired with the antipsychotic drug clozapine, as it can have the opposite effect.
  • Treatment after a Stroke: At small doses (1 or 2 grams), glycine supplements can also potentially mitigate the after-effects of a stroke by reducing the amount of brain damage. Patients should start taking the supplement within a few hours after a stroke, but under a doctor’s supervision, as it is unclear if taking too much can actually cause harm.
  • Help Diabetics Control Blood Sugar: More research needs to be done to confirm this, but initial studies suggest that taking glycine supplements can help people with type 2 diabetes regulate their blood sugar.
  • Possible Cancer-Fighting Properties: Perhaps the most exciting benefit of all that requires the most research is glycine’s potential to fight cancer.
  • Safe for Most Healthy Individuals: Another benefit of glycine supplements is that they are very safe for most healthy people, even at high doses (up to 60 grams).

Although Glycine supplements have many other marketed health benefits such as improving memory and cognitive function, reducing stress, helping kids grow, easing insomnia, and alleviating stomach complaints, little or no research has been done to back up these particular claims.

Are There Any Side Effects?

Glycine is generally a very safe supplement for most people, even when taken at high doses. If anything, the most common negative side effect is that it might not be an effective treatment for the condition you want it to manage, especially if you aren’t careful about which maker you are purchasing the supplement from. However, there are some possible (though rare) side effects to taking glycine supplements.

One rare but possible side effect experienced by the general public are stomach complaints such as nausea, vomiting, and upset stomach. This seems to be the only negative side effect experienced by individuals with no serious health issues, and it doesn’t cause permanent damage.

As mentioned before, glycine supplements should not be taken in conjunction with clozapine, as the combination can worsen symptoms of schizophrenia, and patients who have suffered a stroke should only take this supplement under the advice of their doctor to avoid the risk of causing more damage. Other groups who should consult their doctor before starting a glycine supplement regimen are young children, people with kidney or liver problems, and women who are pregnant or breastfeeding, since it is not currently known how safe these supplements are for these individuals.

How to Take Glycine Supplements

As mentioned before, if you are a healthy individual and aren’t currently taking clozapine, then glycine supplements are extremely safe for you. According to WebMD, you can take glycine in a couple of different ways depending on the condition you want to treat. Most prefer to take glycine supplements in a capsule, but this isn’t the only option.

If you decide to take glycine supplement capsules, start with a smaller dosage. Over time you can gradually increase the dosage until you achieve your desired results, though even if you don’t get the results you are looking for you shouldn’t exceed 60 grams. For people who have suffered a stroke, the recommendation is to dissolve a 1 or 2-gram glycine tablet under the tongue. To treat skin conditions such as leg ulcers, you can even find it in cream form and apply it topically to the skin.

What to Look for in a Good Glycine Supplement

As with any supplement, the most important thing you can do when shopping for a good glycine supplement is to look for a good brand. Since supplements aren’t as heavily regulated as prescription medications, not all brands deliver the same level of quality, so some supplements can have more health benefits than others.

Some research can let you know if a maker has a dedication to using quality ingredients and if others who have purchased the supplement are satisfied with the results. Vegans and vegetarians may also want to pay extra attention to the label to ensure that the supplement only contains plant-based ingredients.

In short, not only does glycine play an integral role in supporting different body systems and functions, at higher doses it can also have some impressive health benefits. Not only is it generally a very safe supplement, it also shows the most promise in treating schizophrenia and reducing brain damage after a stroke in small doses, and some evidence of helping control blood sugar and even prevent cancer. However, this supplement isn’t safe for everyone.

It shouldn’t be combined with the schizophrenia medication clozapine, and pregnant/breastfeeding women as well as those with kidney/liver disease should use caution. Otherwise, higher doses or topical application on the skin are safe. As long as you do your research, you can find a quality supplement that can be safely added to your healthy lifestyle.

Note: Always speak with your doctor before taking any supplements featured on this website. This article has not been written, reviewed or endorsed by a medical professional and may not be used to diagnose or treat any medical conditions.